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Introduction Pragmatic randomized controlled trials (RCTs) mimic usual clinical practice and they are critical to inform decision-making by patients, clinicians and policy-makers in real-world settings. pragmatic 777 Pragmatic RCTs assess effectiveness of available medicines, while explanatory RCTs assess efficacy of investigational medicines. rtp gacor hari ini pragmatic Explanatory and pragmatic are the extremes of a continuum This